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04 June 2021 Coronavirus Charts and News: Could Green Tea Be The Weapon To Prevent COVID-19 Infections? CDC Now Says Fully Vaccinated People Can Skip Routine COVID-19 Testing.

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Written by Steven Hansen

The U.S. new cases 7-day rolling average are 34.7 % LOWER than the 7-day rolling average one week ago and U.S. deaths due to coronavirus are now 37.4 % LOWER than the rolling average one week ago. Today’s posts include:

  • U.S. Coronavirus New Cases are 19,485
  • U.S. Coronavirus deaths are at 614
  • U.S. Coronavirus immunizations have been administered to 88.8 doses per 100 people.
  • The 7-day rolling average rate of growth of the pandemic shows new cases improved and deaths improved
  • COVID, Ivermectin, and the Crime of the Century: DarkHorse Podcast with Pierre Kory & Bret Weinstein
  • The Lab-Leak Theory: Investigating Fauci’s COVID “Can Of Worms”
  • A scientist adventurer and China’s ‘Bat Woman’ are under scrutiny as coronavirus lab-leak theory gets another look
  • Study says COVID-19 vaccines passports will likely reduce inclination to accept vaccines
  • The experimental drug TEMPOL may be a promising oral antiviral treatment for COVID-19
  • FDA authorizes Regeneron’s COVID-19 antibody drug for injections
  • Investigation Pokes Holes in Idea That Smoking Cuts COVID Risks
  • Heart reaction probed as possible rare vaccine link in teens
  • New increases in teen hospitalization rates reinforce importance of Covid-19 vaccination, CDC study says
  • The first Olympic team to touch down in Japan faces constrictions galore
  • Daily increases in the U.S. COVID-19 case count have reached the lowest level since the beginning of the pandemic in March 2020

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Hospitalizations Are The Only Accurate Gauge

Hospitalizations historically appear to be little affected by weekends or holidays. The hospitalization growth rate trend continues to improve.

source: https://gis.cdc.gov/grasp/covidnet/COVID19_3.html

Historically, hospitalization growth follows new case growth by one to two weeks.

As an analyst, I use the rate of growth to determine the trend. But, the size of the pandemic is growing in terms of real numbers – and if the rate of growth does not become negative – the pandemic will overwhelm all resources.

The graph below shows the rate of growth relative to the growth a week earlier updated through today [note that negative numbers mean the rolling averages are LOWER than the rolling averages one week ago]. As one can see, the rate of growth for new cases peaked in early December 2020 for Thanksgiving, and early January 2021 for end-of-year holidays – and it now shows that the coronavirus effect is improving.

In the scheme of things, new cases decline first, followed by hospitalizations, and then deaths. The potential fourth wave did not materialize likely due to immunizations.


Coronavirus News You May Have Missed

Could a green tea compound combat SARS-CoV-2? – News-Medical

The key findings of their study revealed that EGCG activates Nrf2 and suppresses angiotensin-converting enzyme 2 (ACE2), which is a cellular receptor for SARS-CoV-2, and TMPRSS2, a mediator of virus entry into the host cell. EGCG also inactivates SARS-CoV-2 main protease and inhibits viral reproduction. EGCG’s antioxidant activity may offer protection against SARS-CoV-2-induced mitochondrial ROS, which promotes viral replication and against ROS burst caused by neutrophil extracellular traps. EGCG suppresses ER-resident GRP78 activity and expression and can potentially inhibit the life cycle of SARS-CoV-2.

EGCG may suppress SARS-CoV-2 infection via suppressing the expression of cell surface ACE2 and TMPRSS2 via activating Nrf2. EGCG may also inhibit SARS-CoV-2 Mpro — a protease essential for viral reproduction.”

The researchers also found protective effects of EGCG against (a) thrombosis by suppressing tissue factors and activating platelets; (b) cytokine storm-induced acute lung injury/respiratory distress; (c) sepsis via inactivating redox-sensitive HMGB1; and (d) lung fibrosis by augmenting Nrf2 and suppressing NF-κB.

Findings highlight the need for further studies on the role of EGCG in COVID-19 prevention and treatment

To summarize, EGCG may have the potential to inhibit SARS-CoV-2 infection, suppress SARS-CoV-2 replication, decrease cytokine storm and hence thrombosis and lung fibrosis. According to the authors, no such human studies have not been conducted so far. Other catechins in green tea may exhibit similar protective properties as EGCG, possibly at lower levels. Green tea consumption has been previously shown to decrease the risk for diabetes, obesity, and cardiovascular diseases, all of which increase the risk of severe COVID-19.

However, these observations need to be further substantiated in humans and animals. The possible actions of EGCG against SARS-CoV-2 highlight the relevance of further studies on the role of EGCG in COVID-19 prevention and treatment in humans. These observations also warrant epidemiological studies on the possible preventive effects of green tea consumption on COVID-19.

A scientist adventurer and China’s ‘Bat Woman’ are under scrutiny as coronavirus lab-leak theory gets another look – Washington Post

… Nothing is known outside China about the science gleaned from that expedition by the Wuhan CDC — the same agency that oversaw China’s early pandemic response. The team has not disclosed what viruses, if any, it found in the cave, or even when the mission took place. According to a World Health Organization report released in March, the Wuhan CDC denied any storage or laboratory activities involving bat viruses before the coronavirus outbreak — a stance hard to reconcile with Tian’s boasts in the video about having visited dozens of bat caves and studied 300 types of virus vectors.

Tian [Tian Junhua, one of the bat hunters],has not spoken publicly for more than a year.

The silencing of scientists, the blanket denials, the careful guarding of raw data and biological samples — these elements have been emblematic of the approach by Chinese authorities at every stage of the coronavirus outbreak. And they continue to obstruct the world’s ability to get answers.

There is no direct evidence linking Tian’s team, or a rival group of bat-disease specialists at the Wuhan Institute of Virology, to the coronavirus outbreak. Nor is there more than circumstantial evidence to support any theory of the pandemic’s origin. Many scientists say the most likely path is that the virus spread in nature and jumped from animals to humans. But that belief is largely based on how other coronaviruses have originated, not what is known about this case.

The lack of clarity is not in itself alarming at this point in an investigation of virus origins — in the case of severe acute respiratory syndrome (SARS), scientists were fairly quick to identify civet cats as the intermediate host, though it took years to find the bat population that harbored the building blocks of the virus. But the WHO chief, the Biden administration, other governments and scientists around the world have rebuked China for not making this investigation any easier.

[editor’s note: seemingly a balanced post on the origins of COVID-19 which deserves a full read. Also read Analysis: Mounting pressure on China about Covid ‘lab leak’ could backfire]

Heart reaction probed as possible rare vaccine link in teens – AP

Health authorities are trying to determine whether heart inflammation that can occur along with many types of infections could also be a rare side effect in teens and young adults after the second dose of COVID-19 vaccine.

An article on seven U.S. teen boys in several states, published online Friday in Pediatrics, is among the latest reports of heart inflammation discovered after COVID-19 vaccination, though a link to the vaccine has not been proven.

The boys, aged 14 to 19, received Pfizer shots in April or May and developed chest pain within a few days. Heart imaging tests showed a type of heart muscle inflammation called myocarditis.

None were critically ill. All were healthy enough to be sent home after two to six days in the hospital and are doing ”doing pretty well,” said Dr. Preeti Jaggi, an Emory University infectious disease specialist who co-authored the report.

She said more follow-up is needed to determine how the seven fare but that it’s likely the heart changes were temporary.

Only one of the seven boys in the Pediatrics report had evidence of a possible previous COVID-19 infection and doctors determined none of them had a rare inflammatory condition linked with the coronavirus.

The cases echo reports from Israel in young men diagnosed after receiving Pfizer shots.

Investigation Pokes Holes in Idea That Smoking Cuts COVID Risks – MedPage

In the early days of the pandemic, preliminary data out of France suggested that COVID-19 was occurring less frequently in smokers. Studies and articles published in the spring of 2020 contemplated the “unanticipated protective effect on COVID-19 incidence in smokers and a less clear association with disease severity.”

A year on, more evidence has disproved the theory that smoking can have a protective effect against COVID-19; one U.K. study analyzing 17.3 million primary care records found that smokers had a 14% increased chance of COVID-19-related death after controlling for age and sex.

In March, the European Respiratory Journal issued a retraction notice for an article published in July 2020 upon the discovery that some of the authors had failed to disclose their highly relevant financial ties to the tobacco industry. The now-retracted article posited that smokers had a significantly lower risk of getting infected by COVID-19, and that smoking was not associated with adverse outcomes for smokers who did contract the disease.

Among the authors who failed to report their conflicts of interest was Konstantinos Farsalinos, MD, MPH, a Greek cardiologist who has spent years steeped in the world of tobacco harm reduction (THR) research and advocacy.

In an investigation published in The BMJ, French journalist Stéphane Horel and Dutch journalist Ties Keyzer found that, for other journal publications over the years, Farsalinos had disclosed receiving fees and funding from a number of nonprofits and organizations with THR interests, such as the American E-Liquid Manufacturing Standards Association, the Tennessee Smoke Free Association, FlavourArt, and Nobacco.

Since the beginning of the pandemic, Farsalinos, of the University of Patras and University of West Attica in Greece, has led the charge in authoring studies that promote the nicotine benefit hypothesis. And in a re-analysis of smoking prevalence and COVID-19 severity and mortality published in the Harm Reduction Journal in January, he again emphasized the potential benefits that nicotine might have for hospitalized patients.

In its retraction, the European Respiratory Journal also stated that co-author Konstantinos Poulas, PhD, was a principal investigator for a Greek NGO called “NOSMOKE” at the time the article was published. The Greek NGO is based out of Patras Science Park, a science and innovation hub funded by the Foundation for a Smoke-Free World — a nonprofit that was founded in 2017 by Philip Morris International, the largest cigarette manufacturing company in the world.

COVID, Ivermectin, and the Crime of the Century: DarkHorse Podcast with Pierre Kory & Bret Weinstein – YouTube

Mentioned in this episode: British Ivermectin Recommendation Development group: https://bird-group.org The BIRD Recommendation on the Use of Ivermectin for Covid-19: Executive Summary: https://bird-group.org/wp-content/upl… Carvallo et al 2020. Study of the efficacy and safety of topical ivermectin+ iota-carrageenan in the prophylaxis against COVID-19 in health personnel. J. Biomed. Res. Clin. Investig., 2. https://medicalpressopenaccess.com/up… Cobos-Campos et al 2021.Potential use of ivermectin for the treatment and prophylaxis of SARS-CoV-2 infection: Efficacy of ivermectin for SARS-CoV-2. Clin Res Trials, 7: 1-5. https://www.readkong.com/page/potenti… Database of all ivermectin COVID-19 studies. 93 studies, 55 peer reviewed, 56 with results comparing treatment and control groups: https://c19ivermectin.com Karale et al 2021. A Meta-analysis of Mortality, Need for ICU admission, Use of Mechanical Ventilation and Adverse Effects with Ivermectin Use in COVID-19 Patients. medRxiv. https://www.medrxiv.org/content/medrx… Kory et al 2021. Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19. American Journal of Therapeutics, 28(3): e299: https://www.ncbi.nlm.nih.gov/pmc/arti… Nardelli et al 2021. Crying wolf in time of Corona: the strange case of ivermectin and hydroxychloroquine. Is the fear of failure withholding potential life-saving treatment from clinical use?. Signa Vitae, 1: 2. https://oss.signavitae.com/mre-signav… Yagisawa et al 2021. Global trends in clinical studies of ivermectin in COVID-19. The Japanese Journal of Antibiotics, 74: 1. https://www.psychoactif.org/forum/upl…

The Lab-Leak Theory: Investigating Fauci’s COVID “Can Of Worms” – ZeroHedge

Since December 1, 2019, the SARS-CoV-2 virus that causes COVID-19 has infected more than 170 million people around the world and killed more than 3.5 million. To this day, we don’t know how or why this novel coronavirus suddenly appeared in the human population. Answering that question is more than an academic pursuit: Without knowing where it came from, we can’t be sure we’re taking the right steps to prevent a recurrence.

And yet, in the wake of the Lancet statement and under the cloud of Donald Trump’s toxic racism, which contributed to an alarming wave of anti-Asian violence in the U.S., one possible answer to this all-important question remained largely off-limits until the spring of 2021.

Behind closed doors, however, national security and public health experts and officials across a range of departments in the executive branch were locked in high-stakes battles over what could and couldn’t be investigated and made public.

A months long Vanity Fair investigation, interviews with more than 40 people, and a review of hundreds of pages of U.S. government documents, including internal memos, meeting minutes, and email correspondence, found that conflicts of interest, stemming in part from large government grants supporting controversial virology research, hampered the U.S. investigation into COVID-19’s origin at every step. In one State Department meeting, officials seeking to demand transparency from the Chinese government say they were explicitly told by colleagues not to explore the Wuhan Institute of Virology’s gain-of-function research, because it would bring unwelcome attention to U.S. government funding of it.

In an internal memo obtained by Vanity Fair, Thomas DiNanno, former acting assistant secretary of the State Department’s Bureau of Arms Control, Verification, and Compliance, wrote that staff from two bureaus, his own and the Bureau of International Security and Nonproliferation, “warned” leaders within his bureau “not to pursue an investigation into the origin of COVID-19” because it would “‘open a can of worms’ if it continued.”

There are reasons to doubt the lab-leak hypothesis. There is a long, well-documented history of natural spillovers leading to outbreaks, even when the initial and intermediate host animals have remained a mystery for months and years, and some expert virologists say the supposed oddities of the SARS-CoV-2 sequence have been found in nature.

But for most of the past year, the lab-leak scenario was treated not simply as unlikely or even inaccurate but as morally out-of-bounds. In late March, former Centers for Disease Control director Robert Redfield received death threats from fellow scientists after telling CNN that he believed COVID-19 had originated in a lab. “I was threatened and ostracized because I proposed another hypothesis,” Redfield told Vanity Fair. “I expected it from politicians. I didn’t expect it from science.”

With President Trump out of office, it should be possible to reject his xenophobic agenda and still ask why, in all places in the world, did the outbreak begin in the city with a laboratory housing one of the world’s most extensive collection of bat viruses, doing some of the most aggressive research?

Dr. Richard Ebright, board of governors professor of chemistry and chemical biology at Rutgers University, said that from the very first reports of a novel bat-related coronavirus outbreak in Wuhan, it took him “a nanosecond or a picosecond” to consider a link to the Wuhan Institute of Virology. Only two other labs in the world, in Galveston, Texas, and Chapel Hill, North Carolina, were doing similar research. “It’s not a dozen cities,” he said. “It’s three places.”

[editor’s note: this is the tip of the iceberg in this post, and it deserves a full read]

Daily increases in the U.S. COVID-19 case count have reached the lowest level since the beginning of the pandemic in March 2020. – Axios

The U.S. has brought new coronavirus infections down to the lowest level since March 2020, when the pandemic began.

The big picture: Nearly every week for the past 56 weeks, Axios has tracked the change — more often than not, the increase — in new COVID-19 infections. Those case counts are now so low, the virus is so well contained, that this will be our final weekly map.

By the numbers: The U.S. averaged roughly 16,500 new cases per day over the past week, a 30% improvement over the week before. New cases declined in 43 states and held steady in the other seven.

  • The official case counts haven’t been this low since Americans went into lockdown in March last year — when the pandemic was still new, no one knew how long this would go on, and inadequate testing meant that cases were undercounted.

Overall, roughly 33 million Americans — about 10% of the population — have tested positive for COVID-19.

  • About 595,000 people have died from the virus in the U.S., making it deadlier for Americans than the past 80 years of wars and other armed military conflicts combined, including World War II.

NIH researchers identify potential new antiviral drug for COVID-19 – NIH.gov

The experimental drug TEMPOL may be a promising oral antiviral treatment for COVID-19, suggests a study of cell cultures by researchers at the National Institutes of Health. TEMPOL can limit SARS-CoV-2 infection by impairing the activity of a viral enzyme called RNA replicase. The work was led by researchers at NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The study appears in Science.

“We urgently need additional effective, accessible treatments for COVID-19,” said Diana W. Bianchi, M.D., NICHD Director. “An oral drug that prevents SARS-CoV-2 from replicating would be an important tool for reducing the severity of the disease.”

The study team was led by Tracey A. Rouault, M.D., head of the NICHD Section on Human Iron Metabolism. It discovered TEMPOL’s effectiveness by evaluating a more basic question on how the virus uses its RNA replicase, an enzyme that allows SARS-CoV-2 to replicate its genome and make copies of itself once inside a cell.

Researchers tested whether the RNA replicase (specifically the enzyme’s nsp12 subunit) requires iron-sulfur clusters for structural support. Their findings indicate that the SARS-CoV-2 RNA replicase requires two iron-sulfur clusters to function optimally. Earlier studies had mistakenly identified these iron-sulfur cluster binding sites for zinc-binding sites, likely because iron-sulfur clusters degrade easily under standard experimental conditions.

Identifying this characteristic of the RNA replicase also enables researchers to exploit a weakness in the virus. TEMPOL can degrade iron-sulfur clusters, and previous research from the Rouault Lab has shown the drug may be effective in other diseases that involve iron-sulfur clusters. In cell culture experiments with live SARS-CoV-2 virus, the study team found that the drug can inhibit viral replication.

Based on previous animal studies of TEMPOL in other diseases, the study authors noted that the TEMPOL doses used in their antiviral experiments could likely be achieved in tissues that are primary targets for the virus, such as the salivary glands and the lungs.

FDA authorizes Regeneron’s COVID-19 antibody drug for injections – The Hill

The Food and Drug Administration (FDA) has authorized Regeneron’s COVID-19 antibody drug for injections.

Regeneron said in a statement on Friday that the agency updated the emergency use authorization for REGEN-COV, lowering the dose from 2,400 mg to 1,200 mg.

The authorization also says the drug should be administered by intravenous infusion or subcutaneous injection when an infusion is not feasible.

Regeneron said it plans to deliver at least 1 million doses to the federal government by the second quarter of this year. It expects to file for full approval of the drug in non-hospitalized outpatients later this summer.

The company has already received emergency authorization for treating adults with mild to moderate COVID-19 and pediatric patients aged 12 years and older who are at higher risk for progressing to severe COVID-19.

The company said in April that it is planning to ask the FDA to allow the drug to be used as a preventative treatment for COVID-19.

The updated authorization is based on data from several trials, including one which showed the antibody drug reduced the risk of hospitalization or death by 70 percent in high-risk non-hospitalized patients.

Study says COVID-19 vaccines passports will likely reduce inclination to accept vaccines – News-Medical

a new study published on medRxiv* preprint server focuses on the quantitative evaluation of the impact of the implementation of vaccine passports for domestic and international travel.

This study examines whether vaccine passports are likely to encourage or discourage the uptake of COVID-19 vaccines among individuals who have not yet received two doses of a COVID-19 vaccine.

Researchers have computed the overall impact of the induction of vaccine passports on the general intention to be vaccinated. Further, the differential impact of vaccine passports on uptake intent between socio-demographic groups was determined.

… This study highlighted that vaccine passports or certificates are less popular in certain socio-demographic groups such as non-White, Black African, Black Caribbean, and British Muslims, which creates a risk of developing a divided society.

Considering the reluctance to get vaccinated, there is still the possibility that the epidemic will spread. According to the researchers, if this group refuses to get vaccinated, even after attempts to convince them, the rate of vaccination in their adjacent areas should be increased in order to achieve herd immunity.

Researchers have observed that the group of participants who expressed doubts about getting vaccines remained unchanged in their views. They displayed a lower inclination to be vaccinated, after the introduction of vaccine passports.

Further, the health workers and social care workers in the UK stated that as people are feeling pressured to get vaccinated, the actual turnaround was declining.

The survey also reported that most females, professionals, and university degree holders showed a decreased inclination to vaccinate if vaccine passports were to be introduced for domestic use.

The authors of the study stated that there are no specific reasons that explain the difference in the willingness for vaccination. However, the sense of new and unfamiliar scientific phenomena may account for this unwillingness.

This survey found that the general willingness to get vaccinated increased across the UK after the commencement of the vaccination program. However, the impact on getting vaccinated, after introducing vaccine passports, was inconclusive.

CDC: Fully Vaccinated People Can Skip Routine COVID-19 Testing – Medscape

People who have been fully vaccinated against COVID-19 don’t need to be tested regularly or quarantine, even after being exposed to someone who was sick, according to the latest CDC guidance.

At the same time, those who are fully vaccinated should get tested or quarantine if they develop COVID-19 symptoms such as fever, cough, and fatigue.

“Most fully vaccinated people with no COVID-like symptoms do not need to quarantine, be restricted from work, or be tested following an exposure to someone with suspected or confirmed COVID-19, as their risk of infection is low,” the CDC wrote.

“However, they should still monitor for symptoms of COVID-19 for 14 days following an exposure,” the CDC added.

The updated guidance is based on recent studies that show vaccinated people face a very low risk of serious disease, according to the Associated Press. Even if vaccinated individuals get infected, they’re less likely to spread it to others, and they have mild or no symptoms.

This means that vaccinated people can be excluded from routine workplace screenings, the CDC said, though many employers aren’t tracking their employees’ vaccination status. Screening is still recommended for those who work in homeless shelters, prisons, and health care facilities due to the higher risk of COVID-19 outbreaks.

The first Olympic team to touch down in Japan faces constrictions galore. – New York Times

The Australian softball players who arrived in Japan this week for the Tokyo Olympics have spent most of their lives trying to reach the world’s pre-eminent sporting event.

Now they will experience much of their Olympic moment living in small hotel rooms far from Tokyo, being tested daily for the coronavirus and doing gym workouts in groups no larger than six. All fully vaccinated, they cannot go to bars, restaurants or shrines.

The team is the first to touch down in the host country before the Games, which open in seven weeks, and its constricted arrival offers a preview of an Olympics like no other, held as much of the globe remains in the clutches of a deadly pandemic.

New increases in teen hospitalization rates reinforce importance of Covid-19 vaccination, CDC study says – CNN

A recent increase in Covid-19 hospitalizations among people ages 12 to 17 reinforces the importance of practicing prevention measures against the coronavirus and vaccination, according to a study released Friday in the US Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

The report looked at hospitalization data for 12- to- 17-year-olds from a large coronavirus surveillance network. It found 204 adolescents who were likely hospitalized primarily for Covid-19 between Jan. 1 and March 31, 2021. Nearly a third — 31.4% — were admitted to intensive care units and 4.9% required invasive mechanical ventilation. There were no associated deaths.

Hospitalization rates among young people from March 1, 2020 to April 24, 2021 peaked in the week ending Jan. 9 at 2.1 per 100,000, then lowered to 0.6 in the week ending March 13. Rates then rose again to 1.3 and 1.2 respectively for the weeks ending April 17 and April 24.

The trend contrasts with hospitalization rates among people age 65 and older – the group with the highest Covid-19 vaccination coverage. During that period, hospitalization rates stabilized for that older age group

Hospitalization rates for adolescents were lower than rates among adults, but exceeded those among children ages 5 to 11. The recent increase in hospitalization rates among people ages 12 to 17 might be related to more transmissible coronavirus variants, large numbers of children returning to school and other indoor activities, and changes in physical distancing, mask wearing and other prevention behaviors, researchers wrote. The Covid-19 vaccine made by Pfizer was authorized for use in people as young as 12 in May.

Compared with flu-associated hospitalization rates, cumulative Covid-19 associated hospitalization rates from Oct. 1, 2020 to April 24, 2021 were 2.5 to 3.0 times higher than three recent flu seasons.

The following are foreign headlines with hyperlinks to the posts

France reopening to vaccinated Americans June 9

Vaccine programs in Africa are struggling because of funding and vaccine shortages.

“Mexican variant” and monitoring actions of SARS-CoV-2 genome

Swedish Parliament Committee Says Government Failed in Pandemic Handling

COVID-19 Far More Widespread in Indonesia Than Official Data Show: Studies

Russia Warns of ‘Politicization’ of COVID-19 Origin amid U.S.-China Feud

Taiwan’s hospitals are being stretched to their limits as case counts rise.

Vietnam asked its people for cash to help fight the virus — and they delivered.

Travelers returning to the U.K. from Portugal must quarantine starting Tuesday, officials say.

The following additional national and state headlines with hyperlinks to the posts

US government found no evidence that Navy UFO sightings were alien spacecraft: report

California and 11 other states have given 70 percent of residents at least one vaccine dose. Others, especially red states, are falling behind.

Additional Infections Rare in Hospitalized COVID Patients

States Are Passing Laws That Threaten Public Health, Report Finds

‘Mission: Impossible 7’ shut down again due to COVID-19

States with low vaccination rates are “sitting ducks” for the next major COVID-19 outbreak, said NIH Director Francis Collins, MD, PhD.

FDA updated the emergency use authorization for casirivimab-imdevimab, cutting the dose in half for the antibody cocktail while also authorizing a subcutaneous injection for situations where IV infusion isn’t possible or would delay treatment, Regeneron announced.

NIAID Director Anthony Fauci, MD, called on the Chinese government to release the medical records of nine people, including three working at a Wuhan lab who reportedly fell sick weeks before the start of the outbreak there.

Post-COVID-19 assessment shows long-lasting consequences for many non-hospitalized individuals

Study: 7 US teens report heart inflammation after second Pfizer dose

President Biden on Friday made clear he has confidence in his medical adviser Anthony Fauci as conservatives ramp up their attacks on the government’s top infectious diseases expert over his comments on the origins of COVID-19.

Most CA Workers Required to Keep Masks on Unless All Are COVID Vaccinated

COVID Shot Doesn’t Affect Fertility, Changes to Period Short-Lived: Experts

Anti-Vaccine Group Boasts 3,000 Pages of Fauci Emails, Suspended by Twitter

Covid hospitalizations are rare among children, but still more frequent than for flu, the C.D.C. says.

Memorial Day was “the first big stress test” for the US as Americans returned to a sense of normalcy from the Covid-19 pandemic, CNN medical analyst Dr. Leana Wen said. She said it could take another two weeks to determine where the US really stands on its Covid-19 progress.

Today’s Posts On Econintersect Showing Impact Of The Pandemic With Hyperlinks

April 2021 Headline Manufacturing New Orders Declined

May 2021 BLS Jobs Situation – Job Gains Good But On The Low Side Of Expectations

Rail Week Ending 29 May 2021 – May Rail Movements Up 28% Year-over-Year

Warning to Readers

The amount of politically biased articles on the internet continues. And studies and opinions of the experts continue to contradict other studies and expert opinions. Honestly, it is difficult to believe anything anymore.

I assemble this coronavirus update daily – sifting through the posts on the internet. I try to avoid politically slanted posts (mostly from CNN, New York Times, and the Washington Post) and can usually find unslanted posts on that subject from other sources on the internet. I wait to publish posts on subjects that I cannot validate across several sources. But after all this extra work, I do not know if I have conveyed the REAL facts. It is my job to provide information so that you have the facts necessary – and then it is up to readers to draw conclusions.

Analyst Opinion of Coronavirus Data

There are several takeaways that need to be understood when viewing coronavirus statistical data:

  • The global counts are suspect for a variety of reasons including political. Even the U.S. count has issues as it is possible that as much as half the population has had coronavirus and was asymptomatic. It would be a far better metric using a random sampling of the population weekly. In short, we do not understand the size of the error in the tracking numbers.
  • Just because some of the methodology used in aggregating the data in the U.S. is flawed – as long as the flaw is uniformly applied – you establish a baseline. This is why it is dangerous to compare two countries as they likely use different methodologies to determine who has (and who died) from coronavirus.
  • COVID-19 and the flu are different but can have similar symptoms. COVID-19 so far is much more deadly than the flu. [click here to compare symptoms]
  • From an industrial engineering point of view, one can argue that it is best to flatten the curve only to the point that the health care system is barely able to cope. This solution only works if-and-only-if one can catch this coronavirus once and develops immunity. In the case of COVID-19, herd immunity may need to be in the 80% to 85% range. WHO warns that few have developed antibodies to COVID-19 when recovering from COVID-19. Herd immunity does not look like an option as the variants are continuing to look for ways around immunity.
  • Older population countries will have a significantly higher death rate as there is relatively few hospitalizations and deaths in younger age groups..
  • There are at least 8 strains of the coronavirus.

What we do or do not know about the coronavirus [actually there is little scientifically proven information]. Most of our knowledge is anecdotal, from studies with limited subjects, or from studies without peer review.

  • How many people have been infected as many do not show symptoms?
  • Masks do work. Unfortunately, early in the pandemic, many health experts — in the U.S. and around the world — decided that the public could not be trusted to hear the truth about masks. Instead, the experts spread a misleading message, discouraging the use of masks.
  • Current thinking is that we develop at least 12 months of immunity from further COVID infection.
  • The Moderna and Pfizer vaccines have an effectiveness rate of about 95 percent after two doses. That is on par with the vaccines for chickenpox and measles. The 95 percent number understates the effectiveness as it counts anyone who came down with a mild case of Covid-19 as a failure.
  • To what degree do people who never develop symptoms contribute to transmission? Research early in the pandemic suggested that the rate of asymptomatic infections could be as high as 81%. But a meta-analysis, which included 13 studies involving 21,708 people, calculated the rate of asymptomatic presentation to be 17%.
  • The accuracy of rapid testing is questioned – and the more accurate test results are not being given in a timely manner.
  • Can children widely spread coronavirus? [current thinking is that they are a minor source of the pandemic spread]
  • Why have some places avoided big coronavirus outbreaks – and others hit hard?
  • Air conditioning contributes to the pandemic spread.
  • It appears that there is increased risk of infection and mortality for those living in larger occupancy households.
  • Male patients have almost three times the odds of requiring intensive treatment unit (ITU) admission compared to females.
  • Outdoor activities seem to be a lower risk than indoor activities.

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